David Grisman's bands in their various quartet and quintet configurations, have showcased acoustic music ever since he started the first DGQ in the fall of 1975. That band featured David on mandolin, Todd Phillips on mandolin, Joe Carroll on bass, Tony Rice on guitar, and Darol Anger on fiddle. Ever since then, the DGQ has been the leading force in establishing his new genre of instrumental acoustic string music.

Through the years, the DGQ has been a breeding ground for new acoustic talent. Band alumni including guitarist Tony Rice, Nashville super session picker and Grammy Award winner, Mark O'Conner, Mike Marshall of the "Modern Mandolin Quartet" and Darol Anger of the "Turtle Island String Quartet." Grisman's bands have also had a strong impact on the new generation of musicians, like banjo phenomenon Bela Fleck who saw a traditional bluegrass instrument like the Mandolin being taken beyond the bounds of one idiom.

The current David Grisman Quintet includes David on mandolin, Jim Kerwin on bass, George Marsh on percussion, Frank Vignola on guitar, and Matt Eakle on flute.